Cargando…
Exploring the dual effect of novel 1,4-diarylpyranopyrazoles as antiviral and anti-inflammatory for the management of SARS-CoV-2 and associated inflammatory symptoms
COVID-19 and associated substantial inflammations continue to threaten humankind triggering death worldwide. So, the development of new effective antiviral and anti-inflammatory medications is a major scientific goal. Pyranopyrazoles have occupied a crucial position in medicinal chemistry because of...
Autores principales: | Malebari, Azizah M., E. A. Ahmed, Hany, Ihmaid, Saleh K., Omar, Abdelsattar M., Muhammad, Yosra A., Althagfan, Sultan S., Aljuhani, Naif, A. A. El-Sayed, Abdel-Aziz, Halawa, Ahmed H., El-Tahir, Heba M., Turkistani, Safaa A., Almaghrabi, Mohammed, K. B. Aljohani, Ahmed, El-Agrody, Ahmed M., Abulkhair, Hamada S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671780/ https://www.ncbi.nlm.nih.gov/pubmed/36403336 http://dx.doi.org/10.1016/j.bioorg.2022.106255 |
Ejemplares similares
-
In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-M(Pro) inhibitors
por: Aljuhani, Ateyatallah, et al.
Publicado: (2022) -
Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect
por: Ahmed, Hany E. A., et al.
Publicado: (2018) -
Synthesis, Modelling, and Anticonvulsant Studies of New Quinazolines Showing Three Highly Active Compounds with Low Toxicity and High Affinity to the GABA-A Receptor
por: Zayed, Mohamed F., et al.
Publicado: (2017) -
Insights on Cancer Cell Inhibition, Subcellular Activities, and Kinase Profile of Phenylacetamides Pending 1H-Imidazol-5-One Variants
por: Khayat, Maan T., et al.
Publicado: (2022) -
SAR Probing of KX2-391 Provided Analogues With Juxtaposed Activity Profile Against Major Oncogenic Kinases
por: Omar, Abdelsattar M., et al.
Publicado: (2022)