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A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice
The progressive decline of physiological function and the increased risk of age-related diseases challenge healthy aging. Multiple anti-aging manipulations, such as senolytics, have proven beneficial for health; however, the biomarkers that label in vivo senescence at systemic levels are lacking, th...
Autores principales: | Sun, Jie, Wang, Ming, Zhong, Yaqi, Ma, Xuan, Sun, Shimin, Xu, Chenzhong, Peng, Linyuan, Li, Guo, Zhang, Liting, Liu, Zuojun, Ai, Ding, Liu, Baohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671911/ https://www.ncbi.nlm.nih.gov/pubmed/36396643 http://dx.doi.org/10.1038/s41467-022-34801-9 |
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