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Bioinformatics analysis of miRNAs in the neuroblastoma 11q-deleted region reveals a role of miR-548l in both 11q-deleted and MYCN amplified tumour cells

Neuroblastoma is a childhood tumour that is responsible for approximately 15% of all childhood cancer deaths. Neuroblastoma tumours with amplification of the oncogene MYCN are aggressive, however, another aggressive subgroup without MYCN amplification also exists; rather, they have a deleted region...

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Detalles Bibliográficos
Autores principales: Jurcevic, Sanja, Keane, Simon, Borgmästars, Emmy, Lubovac-Pilav, Zelmina, Ejeskär, Katarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671919/
https://www.ncbi.nlm.nih.gov/pubmed/36396668
http://dx.doi.org/10.1038/s41598-022-24140-6