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TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks

Meiosis requires the formation of programmed DNA double strand breaks (DSBs), essential for fertility and for generating genetic diversity. DSBs are induced by the catalytic activity of the TOPOVIL complex formed by SPO11 and TOPOVIBL. To ensure genomic integrity, DNA cleavage activity is tightly re...

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Detalles Bibliográficos
Autores principales:	Nore, Alexandre, Juarez-Martinez, Ariadna B., Clément, Julie, Brun, Christine, Diagouraga, Boubou, Laroussi, Hamida, Grey, Corinne, Bourbon, Henri Marc, Kadlec, Jan, Robert, Thomas, de Massy, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671922/ https://www.ncbi.nlm.nih.gov/pubmed/36396648 http://dx.doi.org/10.1038/s41467-022-34799-0

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