A lineage tree-based hidden Markov model quantifies cellular heterogeneity and plasticity

Individual cells can assume a variety of molecular and phenotypic states and recent studies indicate that cells can rapidly adapt in response to therapeutic stress. Such phenotypic plasticity may confer resistance, but also presents opportunities to identify molecular programs that could be targeted...

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Detalles Bibliográficos
Autores principales: Mohammadi, Farnaz, Visagan, Shakthi, Gross, Sean M., Karginov, Luka, Lagarde, J. C., Heiser, Laura M., Meyer, Aaron S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671968/
https://www.ncbi.nlm.nih.gov/pubmed/36396800
http://dx.doi.org/10.1038/s42003-022-04208-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671968/
https://www.ncbi.nlm.nih.gov/pubmed/36396800
http://dx.doi.org/10.1038/s42003-022-04208-9

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