Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter

AA amyloidosis is a systemic disease characterized by deposition of misfolded serum amyloid A protein (SAA) into cross-β amyloid in multiple organs in humans and animals. AA amyloidosis occurs at high SAA serum levels during chronic inflammation. Prion-like transmission was reported as possible caus...

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Detalles Bibliográficos
Autores principales: Schulte, Tim, Chaves-Sanjuan, Antonio, Mazzini, Giulia, Speranzini, Valentina, Lavatelli, Francesca, Ferri, Filippo, Palizzotto, Carlo, Mazza, Maria, Milani, Paolo, Nuvolone, Mario, Vogt, Anne-Cathrine, Vogel, Monique, Palladini, Giovanni, Merlini, Giampaolo, Bolognesi, Martino, Ferro, Silvia, Zini, Eric, Ricagno, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672049/
https://www.ncbi.nlm.nih.gov/pubmed/36396658
http://dx.doi.org/10.1038/s41467-022-34743-2

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