Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis

Severe diseases like cirrhosis and liver failure can be developed from primary biliary cholangitis (PBC). Endothelin-2 (EDN2) and endothelin receptor B (EDNRB) are related to the pathogenesis of PBC. However, the roles of EDN2 and EDNRB in PBC-related liver injury and inflammation along with molecul...

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Detalles Bibliográficos
Autores principales: Xu, Guoxin, Gong, Yanping, Lu, Fenying, Wang, Bin, Yang, Zaixing, Chen, Long, Min, Jingyu, Cheng, Cuie, Jiang, Tingwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672122/
https://www.ncbi.nlm.nih.gov/pubmed/36396948
http://dx.doi.org/10.1038/s41598-022-21816-x

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