Therapeutic strategies for intracerebral hemorrhage

Stroke is the second highest cause of death globally, with an increasing incidence in developing countries. Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes. ICH is associated with poor neurological outcomes and high mortality due to the combination of primary and secondary injury....

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Autores principales: Li, Zhe, Khan, Suliman, Liu, Yang, Wei, Ruixue, Yong, V. Wee, Xue, Mengzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672341/
https://www.ncbi.nlm.nih.gov/pubmed/36408517
http://dx.doi.org/10.3389/fneur.2022.1032343
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author Li, Zhe
Khan, Suliman
Liu, Yang
Wei, Ruixue
Yong, V. Wee
Xue, Mengzhou
author_facet Li, Zhe
Khan, Suliman
Liu, Yang
Wei, Ruixue
Yong, V. Wee
Xue, Mengzhou
author_sort Li, Zhe
collection PubMed
description Stroke is the second highest cause of death globally, with an increasing incidence in developing countries. Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes. ICH is associated with poor neurological outcomes and high mortality due to the combination of primary and secondary injury. Fortunately, experimental therapies are available that may improve functional outcomes in patients with ICH. These therapies targeting secondary brain injury have attracted substantial attention in their translational potential. Here, we summarize recent advances in therapeutic strategies and directions for ICH and discuss the barriers and issues that need to be overcome to improve ICH prognosis.
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spelling pubmed-96723412022-11-19 Therapeutic strategies for intracerebral hemorrhage Li, Zhe Khan, Suliman Liu, Yang Wei, Ruixue Yong, V. Wee Xue, Mengzhou Front Neurol Neurology Stroke is the second highest cause of death globally, with an increasing incidence in developing countries. Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes. ICH is associated with poor neurological outcomes and high mortality due to the combination of primary and secondary injury. Fortunately, experimental therapies are available that may improve functional outcomes in patients with ICH. These therapies targeting secondary brain injury have attracted substantial attention in their translational potential. Here, we summarize recent advances in therapeutic strategies and directions for ICH and discuss the barriers and issues that need to be overcome to improve ICH prognosis. Frontiers Media S.A. 2022-11-04 /pmc/articles/PMC9672341/ /pubmed/36408517 http://dx.doi.org/10.3389/fneur.2022.1032343 Text en Copyright © 2022 Li, Khan, Liu, Wei, Yong and Xue. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Li, Zhe
Khan, Suliman
Liu, Yang
Wei, Ruixue
Yong, V. Wee
Xue, Mengzhou
Therapeutic strategies for intracerebral hemorrhage
title Therapeutic strategies for intracerebral hemorrhage
title_full Therapeutic strategies for intracerebral hemorrhage
title_fullStr Therapeutic strategies for intracerebral hemorrhage
title_full_unstemmed Therapeutic strategies for intracerebral hemorrhage
title_short Therapeutic strategies for intracerebral hemorrhage
title_sort therapeutic strategies for intracerebral hemorrhage
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672341/
https://www.ncbi.nlm.nih.gov/pubmed/36408517
http://dx.doi.org/10.3389/fneur.2022.1032343
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AT yongvwee therapeuticstrategiesforintracerebralhemorrhage
AT xuemengzhou therapeuticstrategiesforintracerebralhemorrhage

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