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Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial

INTRODUCTION: This study aimed to evaluate the effectiveness of using muscle relaxant on the ease of laryngeal mask airway (LMA) insertion and possibility of its related complications. METHODS: This double-blind, randomized clinical trial was performed on 60 children aged 1–4 years with ASA (America...

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Autores principales: Totonchi, Ziae, Seyed Siamdoust, Seyed Alireza, Zaman, Behrooz, Rokhtabnak, Faranak, Alavi, Seyyed Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672355/
https://www.ncbi.nlm.nih.gov/pubmed/36406720
http://dx.doi.org/10.1016/j.heliyon.2022.e11504
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author Totonchi, Ziae
Seyed Siamdoust, Seyed Alireza
Zaman, Behrooz
Rokhtabnak, Faranak
Alavi, Seyyed Amin
author_facet Totonchi, Ziae
Seyed Siamdoust, Seyed Alireza
Zaman, Behrooz
Rokhtabnak, Faranak
Alavi, Seyyed Amin
author_sort Totonchi, Ziae
collection PubMed
description INTRODUCTION: This study aimed to evaluate the effectiveness of using muscle relaxant on the ease of laryngeal mask airway (LMA) insertion and possibility of its related complications. METHODS: This double-blind, randomized clinical trial was performed on 60 children aged 1–4 years with ASA (American Society of Anesthesiology) I or II with upper limb injuries who were candidates for surgery. The patients were randomly allocated to the two groups receiving atracurium group as muscle relaxant (MR) or saline group (S). RESULTS: Regarding ease of placement, the LMA was inserted in 66.7% and 63.3% of patients straightforwardly in the MR and S groups, respectively. While it was performed with one maneuver in 23.3% and 26.7% of cases in the MR and S groups, respectively (p = 0.955). Moreover, LMA dislodgment in the two groups was 36.7% in the MR group and 20.0% in the S group without a meaningful difference (P = 0.152). The only complication observed in the two groups was laryngospasm, which occurred in 0.10% and 13.3% in the MR and S groups, respectively (p = 0.688). CONCLUSION: In some pediatric anesthesia, the use of atracurium, as a muscle relaxant had no significant effect on capability of LMA insertion, maintaining airway patency, LMA seal pressure and oxygenation variations. Moreover, it did not have a preventive effect on the occurrence of complications such as laryngospasm.
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spelling pubmed-96723552022-11-19 Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial Totonchi, Ziae Seyed Siamdoust, Seyed Alireza Zaman, Behrooz Rokhtabnak, Faranak Alavi, Seyyed Amin Heliyon Research Article INTRODUCTION: This study aimed to evaluate the effectiveness of using muscle relaxant on the ease of laryngeal mask airway (LMA) insertion and possibility of its related complications. METHODS: This double-blind, randomized clinical trial was performed on 60 children aged 1–4 years with ASA (American Society of Anesthesiology) I or II with upper limb injuries who were candidates for surgery. The patients were randomly allocated to the two groups receiving atracurium group as muscle relaxant (MR) or saline group (S). RESULTS: Regarding ease of placement, the LMA was inserted in 66.7% and 63.3% of patients straightforwardly in the MR and S groups, respectively. While it was performed with one maneuver in 23.3% and 26.7% of cases in the MR and S groups, respectively (p = 0.955). Moreover, LMA dislodgment in the two groups was 36.7% in the MR group and 20.0% in the S group without a meaningful difference (P = 0.152). The only complication observed in the two groups was laryngospasm, which occurred in 0.10% and 13.3% in the MR and S groups, respectively (p = 0.688). CONCLUSION: In some pediatric anesthesia, the use of atracurium, as a muscle relaxant had no significant effect on capability of LMA insertion, maintaining airway patency, LMA seal pressure and oxygenation variations. Moreover, it did not have a preventive effect on the occurrence of complications such as laryngospasm. Elsevier 2022-11-13 /pmc/articles/PMC9672355/ /pubmed/36406720 http://dx.doi.org/10.1016/j.heliyon.2022.e11504 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Totonchi, Ziae
Seyed Siamdoust, Seyed Alireza
Zaman, Behrooz
Rokhtabnak, Faranak
Alavi, Seyyed Amin
Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title_full Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title_fullStr Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title_full_unstemmed Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title_short Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
title_sort comparison of laryngeal mask airway (lma) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672355/
https://www.ncbi.nlm.nih.gov/pubmed/36406720
http://dx.doi.org/10.1016/j.heliyon.2022.e11504
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