Rb1 negatively regulates bone formation and remodeling through inhibiting transcriptional regulation of YAP in Glut1 and OPG expression and glucose metabolism in male mice

OBJECTIVE: Bone is a highly dynamic organ that undergoes constant bone formation and remodeling, and glucose as a major nutrient is necessary for bone formation and remodeling. Retinoblastoma (Rb1) is a critical regulator of mesenchymal stem cells (MSCs) fate, but how Rb1 regulates bone formation an...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yang, Yang, Shuting, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672361/
https://www.ncbi.nlm.nih.gov/pubmed/36343919
http://dx.doi.org/10.1016/j.molmet.2022.101630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672361/
https://www.ncbi.nlm.nih.gov/pubmed/36343919
http://dx.doi.org/10.1016/j.molmet.2022.101630

Ejemplares similares