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Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
The thyroid gland captures iodide in order to synthesize hormones that act on almost all tissues and are essential for normal growth and metabolism. Low plasma levels of thyroid hormones lead to hypothyroidism, which is one of the most common disorder in humans and is not always satisfactorily treat...
Autores principales: | Romitti, Mírian, Tourneur, Adrien, de Faria da Fonseca, Barbara, Doumont, Gilles, Gillotay, Pierre, Liao, Xiao-Hui, Eski, Sema Elif, Van Simaeys, Gaetan, Chomette, Laura, Lasolle, Helene, Monestier, Olivier, Kasprzyk, Dominika Figini, Detours, Vincent, Singh, Sumeet Pal, Goldman, Serge, Refetoff, Samuel, Costagliola, Sabine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672394/ https://www.ncbi.nlm.nih.gov/pubmed/36396935 http://dx.doi.org/10.1038/s41467-022-34776-7 |
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