Cargando…
TrkA(+) Neurons Induce Pathologic Regeneration After Soft Tissue Trauma
Heterotopic ossification (HO) is a dynamic, complex pathologic process that often occurs after severe polytrauma trauma, resulting in an abnormal mesenchymal stem cell differentiation leading to ectopic bone growth in soft-tissues including tendons, ligaments, and muscles. The abnormal bone structur...
Autores principales: | Cherief, Masnsen, Negri, Stefano, Qin, Qizhi, Pagani, Chase A, Lee, Seungyong, Yang, Yunzhi Peter, Clemens, Thomas L, Levi, Benjamin, James, Aaron W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672853/ https://www.ncbi.nlm.nih.gov/pubmed/36222619 http://dx.doi.org/10.1093/stcltm/szac073 |
Ejemplares similares
-
Systemic DKK1 neutralization enhances human adipose‐derived stem cell mediated bone repair
por: Negri, Stefano, et al.
Publicado: (2020) -
NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
por: Lee, Seungyong, et al.
Publicado: (2021) -
Neuron-to-vessel signaling is a required feature of aberrant stem cell commitment after soft tissue trauma
por: Qin, Qizhi, et al.
Publicado: (2022) -
Acetabular Reaming Is a Reliable Model to Produce and Characterize Periarticular Heterotopic Ossification of the Hip
por: Negri, Stefano, et al.
Publicado: (2022) -
Human perivascular stem cells prevent bone graft resorption in osteoporotic contexts by inhibiting osteoclast formation
por: Negri, Stefano, et al.
Publicado: (2020)