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Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161)
Maize MON 87429 was developed to confer tolerance to dicamba, glufosinate, quizalofop and 2,4‐D herbicides. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672889/ https://www.ncbi.nlm.nih.gov/pubmed/36415855 http://dx.doi.org/10.2903/j.efsa.2022.7589 |
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author | Mullins, Ewen Bresson, Jean‐Louis Dalmay, Tamas Dewhurst, Ian Crawford Epstein, Michelle M Firbank, Leslie George Guerche, Philippe Hejatko, Jan Moreno, Francisco Javier Naegeli, Hanspeter Nogué, Fabien Rostoks, Nils Serrano, Jose Juan Sánchez Savoini, Giovanni Veromann, Eve Veronesi, Fabio Ardizzone, Michele Camargo, Ana Martin de Sanctis, Giacomo Federici, Silvia Dumont, Antonio Fernandez Gennaro, Andrea Ruiz, Jose Angel Gomez Goumperis, Tilemachos Kagkli, Dafni Maria Lanzoni, Anna Lewandowska, Aleksandra Lenzi, Paolo Neri, Franco Maria Papadopoulou, Nikoletta Paraskevopoulos, Konstantinos Piffanelli, Pietro Raffaello, Tommaso Streissl, Franz |
author_facet | Mullins, Ewen Bresson, Jean‐Louis Dalmay, Tamas Dewhurst, Ian Crawford Epstein, Michelle M Firbank, Leslie George Guerche, Philippe Hejatko, Jan Moreno, Francisco Javier Naegeli, Hanspeter Nogué, Fabien Rostoks, Nils Serrano, Jose Juan Sánchez Savoini, Giovanni Veromann, Eve Veronesi, Fabio Ardizzone, Michele Camargo, Ana Martin de Sanctis, Giacomo Federici, Silvia Dumont, Antonio Fernandez Gennaro, Andrea Ruiz, Jose Angel Gomez Goumperis, Tilemachos Kagkli, Dafni Maria Lanzoni, Anna Lewandowska, Aleksandra Lenzi, Paolo Neri, Franco Maria Papadopoulou, Nikoletta Paraskevopoulos, Konstantinos Piffanelli, Pietro Raffaello, Tommaso Streissl, Franz |
collection | PubMed |
description | Maize MON 87429 was developed to confer tolerance to dicamba, glufosinate, quizalofop and 2,4‐D herbicides. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize MON 87429 and its conventional counterpart needs further assessment, except for the levels of phytic acid in grains, which do not raise nutritional and safety concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the DMO, PAT, FT_T and CP4 EPSPS proteins as expressed in maize MON 87429. The GMO Panel finds no evidence that the genetic modification impacts the overall safety of maize MON 87429. In the context of this application, the consumption of food and feed from maize MON 87429 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize MON 87429 is as safe as the conventional counterpart and non‐GM maize reference varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize MON 87429 grains into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 87429. The GMO Panel concludes that maize MON 87429, as described in this application, is as safe as its conventional counterpart and the tested non‐GM maize reference varieties with respect to potential effects on human and animal health and the environment. |
format | Online Article Text |
id | pubmed-9672889 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-96728892022-11-21 Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) Mullins, Ewen Bresson, Jean‐Louis Dalmay, Tamas Dewhurst, Ian Crawford Epstein, Michelle M Firbank, Leslie George Guerche, Philippe Hejatko, Jan Moreno, Francisco Javier Naegeli, Hanspeter Nogué, Fabien Rostoks, Nils Serrano, Jose Juan Sánchez Savoini, Giovanni Veromann, Eve Veronesi, Fabio Ardizzone, Michele Camargo, Ana Martin de Sanctis, Giacomo Federici, Silvia Dumont, Antonio Fernandez Gennaro, Andrea Ruiz, Jose Angel Gomez Goumperis, Tilemachos Kagkli, Dafni Maria Lanzoni, Anna Lewandowska, Aleksandra Lenzi, Paolo Neri, Franco Maria Papadopoulou, Nikoletta Paraskevopoulos, Konstantinos Piffanelli, Pietro Raffaello, Tommaso Streissl, Franz EFSA J Scientific Opinion Maize MON 87429 was developed to confer tolerance to dicamba, glufosinate, quizalofop and 2,4‐D herbicides. The molecular characterisation data and bioinformatic analyses do not identify issues requiring food/feed safety assessment. None of the identified differences in the agronomic/phenotypic and compositional characteristics tested between maize MON 87429 and its conventional counterpart needs further assessment, except for the levels of phytic acid in grains, which do not raise nutritional and safety concerns. The GMO Panel does not identify safety concerns regarding the toxicity and allergenicity of the DMO, PAT, FT_T and CP4 EPSPS proteins as expressed in maize MON 87429. The GMO Panel finds no evidence that the genetic modification impacts the overall safety of maize MON 87429. In the context of this application, the consumption of food and feed from maize MON 87429 does not represent a nutritional concern in humans and animals. The GMO Panel concludes that maize MON 87429 is as safe as the conventional counterpart and non‐GM maize reference varieties tested, and no post‐market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize MON 87429 grains into the environment, this would not raise environmental safety concerns. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of maize MON 87429. The GMO Panel concludes that maize MON 87429, as described in this application, is as safe as its conventional counterpart and the tested non‐GM maize reference varieties with respect to potential effects on human and animal health and the environment. John Wiley and Sons Inc. 2022-11-18 /pmc/articles/PMC9672889/ /pubmed/36415855 http://dx.doi.org/10.2903/j.efsa.2022.7589 Text en © 2022 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Mullins, Ewen Bresson, Jean‐Louis Dalmay, Tamas Dewhurst, Ian Crawford Epstein, Michelle M Firbank, Leslie George Guerche, Philippe Hejatko, Jan Moreno, Francisco Javier Naegeli, Hanspeter Nogué, Fabien Rostoks, Nils Serrano, Jose Juan Sánchez Savoini, Giovanni Veromann, Eve Veronesi, Fabio Ardizzone, Michele Camargo, Ana Martin de Sanctis, Giacomo Federici, Silvia Dumont, Antonio Fernandez Gennaro, Andrea Ruiz, Jose Angel Gomez Goumperis, Tilemachos Kagkli, Dafni Maria Lanzoni, Anna Lewandowska, Aleksandra Lenzi, Paolo Neri, Franco Maria Papadopoulou, Nikoletta Paraskevopoulos, Konstantinos Piffanelli, Pietro Raffaello, Tommaso Streissl, Franz Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title | Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title_full | Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title_fullStr | Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title_full_unstemmed | Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title_short | Assessment of genetically modified Maize MON 87429 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2019‐161) |
title_sort | assessment of genetically modified maize mon 87429 for food and feed uses, under regulation (ec) no 1829/2003 (application efsa‐gmo‐nl‐2019‐161) |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672889/ https://www.ncbi.nlm.nih.gov/pubmed/36415855 http://dx.doi.org/10.2903/j.efsa.2022.7589 |
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