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Polymer-tethered glyconanoparticle colourimetric biosensors for lectin binding: structural and experimental parameters to ensure a robust output

Glycan–lectin interactions play essential roles in biology; as the site of attachment for pathogens, cell–cell communication, and as crucial players in the immune system. Identifying if a new glycan (natural or unnatural) binds a protein partner, or if a new protein (or mutant) binds a glycan remain...

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Detalles Bibliográficos
Autores principales: Micallef, Julian, Baker, Alexander N., Richards, Sarah-Jane, Soutar, Douglas E., Georgiou, Panagiotis G., Walker, Marc, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672907/
https://www.ncbi.nlm.nih.gov/pubmed/36425181
http://dx.doi.org/10.1039/d2ra06265h