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Biomarkers in Psychiatric Disorders
Central and peripheral biomarkers can be used to diagnose, treat, and potentially prevent major psychiatric disorders. But there is uncertainty about the role of these biological signatures in neural pathophysiology, and their clinical significance has yet to be firmly established. Psychomotor, cogn...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cambridge University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672933/ https://www.ncbi.nlm.nih.gov/pubmed/36398503 http://dx.doi.org/10.1017/S0963180122000056 |
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author | Glannon, Walter |
author_facet | Glannon, Walter |
author_sort | Glannon, Walter |
collection | PubMed |
description | Central and peripheral biomarkers can be used to diagnose, treat, and potentially prevent major psychiatric disorders. But there is uncertainty about the role of these biological signatures in neural pathophysiology, and their clinical significance has yet to be firmly established. Psychomotor, cognitive, affective, and volitional impairment in these disorders results from the interaction between neural, immune, endocrine, and enteric systems, which in turn are influenced by a person’s interaction with the environment. Biomarkers may be a critical component of this process. The identification and interpretation of biomarkers also raise ethical and social questions. This article analyzes and discusses these aspects of biomarkers and how advances in biomarker research could contribute to personalized psychiatry that could prevent or mitigate the effects of these disorders. |
format | Online Article Text |
id | pubmed-9672933 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-96729332022-11-29 Biomarkers in Psychiatric Disorders Glannon, Walter Camb Q Healthc Ethics Research Article Central and peripheral biomarkers can be used to diagnose, treat, and potentially prevent major psychiatric disorders. But there is uncertainty about the role of these biological signatures in neural pathophysiology, and their clinical significance has yet to be firmly established. Psychomotor, cognitive, affective, and volitional impairment in these disorders results from the interaction between neural, immune, endocrine, and enteric systems, which in turn are influenced by a person’s interaction with the environment. Biomarkers may be a critical component of this process. The identification and interpretation of biomarkers also raise ethical and social questions. This article analyzes and discusses these aspects of biomarkers and how advances in biomarker research could contribute to personalized psychiatry that could prevent or mitigate the effects of these disorders. Cambridge University Press 2022-10 /pmc/articles/PMC9672933/ /pubmed/36398503 http://dx.doi.org/10.1017/S0963180122000056 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. |
spellingShingle | Research Article Glannon, Walter Biomarkers in Psychiatric Disorders |
title | Biomarkers in Psychiatric Disorders |
title_full | Biomarkers in Psychiatric Disorders |
title_fullStr | Biomarkers in Psychiatric Disorders |
title_full_unstemmed | Biomarkers in Psychiatric Disorders |
title_short | Biomarkers in Psychiatric Disorders |
title_sort | biomarkers in psychiatric disorders |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672933/ https://www.ncbi.nlm.nih.gov/pubmed/36398503 http://dx.doi.org/10.1017/S0963180122000056 |
work_keys_str_mv | AT glannonwalter biomarkersinpsychiatricdisorders |