Parkinson disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila

Some Parkinson’s disease (PD)-causative/risk genes, including the PD-associated kinase leucine-rich repeat kinase 2 (LRRK2), are involved in membrane dynamics. Although LRRK2 and other PD-associated genes are believed to regulate synaptic functions, axonal transport, and endolysosomal activity, it r...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoshita, Tsuyoshi, Liu, Jun-Yi, Taniguchi, Daisuke, Ishii, Ryota, Shiba-Fukushima, Kahori, Hattori, Nobutaka, Imai, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
https://www.ncbi.nlm.nih.gov/pubmed/36404922
http://dx.doi.org/10.1016/j.isci.2022.105476

Ejemplares similares

Ejemplares similares