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Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study

BACKGROUND: Nowadays, coronavirus disease is a leading cause of death. Therefore, the study aimed to assess the time to recovery and its predictors among Covid-19 positive patients. METHODS: A hospital-based retrospective cohort study was conducted among 300 COVID-19 patients admitted to Southwester...

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Autores principales: Tsegaye, Serkalem, Bekele, Firomsa, Lulu, Yohanes, Debele, Gebiso Roba, Bekana, Teshome, Tolesa, Leta Deressa, Bidira, Kebebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673091/
https://www.ncbi.nlm.nih.gov/pubmed/36415676
http://dx.doi.org/10.1016/j.amsu.2022.104917
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author Tsegaye, Serkalem
Bekele, Firomsa
Lulu, Yohanes
Debele, Gebiso Roba
Bekana, Teshome
Tolesa, Leta Deressa
Bidira, Kebebe
author_facet Tsegaye, Serkalem
Bekele, Firomsa
Lulu, Yohanes
Debele, Gebiso Roba
Bekana, Teshome
Tolesa, Leta Deressa
Bidira, Kebebe
author_sort Tsegaye, Serkalem
collection PubMed
description BACKGROUND: Nowadays, coronavirus disease is a leading cause of death. Therefore, the study aimed to assess the time to recovery and its predictors among Covid-19 positive patients. METHODS: A hospital-based retrospective cohort study was conducted among 300 COVID-19 patients admitted to Southwestern Ethiopian hospital COVID-19 treatment centers from August 7, 2020 to February 7, 2022. Kaplan Meier was used to estimate the survival time and the Log-rank test was used to compare the survival time between groups of categorical variables. The multivariable survival regression model was used to identify a significant predictor of time to recovery among COVID-19 patients at a P value ⩽ 0.05 with a 95% CI. RESULT: In this study, 92% of patients admitted to Jimma University COVID-19 treatment center and Mettu Karl Comprehensive Specialized Hospital COVID-19 treatment center were recovered from COVID-19 after a maximum of 33 days of follow-up. The overall incidence density was 11.99/100 PD (person day) with a 95% CI of [11.273, 12.719] per 100 PD after a total of 3452 PD observations. The median time of recovery from COVID-19 was 10 days. Age (AHR = 1.945, 95% CI: 1.157, 3.268), hypertension (AHR = 1.856, 95% CI, 1.30, 2.63), diabetes (AHR = 1.406, 95% CI, 1.05, 1.84), being critical (0.298, 2039, 0.434), cancer (AHR = 3.050, 95% CI, 1.172, 7.943), and tuberculosis (AHR = 2.487, 95% CI, 1.504, 4.110) were found to be independent predictors of time to recovery of COVID-19 patients. CONCLUSION: A total of 92% of patients were recovered within 10 days of the median time. Age, hypertension, diabetes mellitus, tuberculosis, severity of the case, cancer, and the presence of acute kidney injury were predictors of recovery time of COVID-19 patients. Therefore, healthcare providers should give strict follow-up and priority to elderly patients with chronic illnesses and those under supportive care.
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spelling pubmed-96730912022-11-18 Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study Tsegaye, Serkalem Bekele, Firomsa Lulu, Yohanes Debele, Gebiso Roba Bekana, Teshome Tolesa, Leta Deressa Bidira, Kebebe Ann Med Surg (Lond) Cohort Study BACKGROUND: Nowadays, coronavirus disease is a leading cause of death. Therefore, the study aimed to assess the time to recovery and its predictors among Covid-19 positive patients. METHODS: A hospital-based retrospective cohort study was conducted among 300 COVID-19 patients admitted to Southwestern Ethiopian hospital COVID-19 treatment centers from August 7, 2020 to February 7, 2022. Kaplan Meier was used to estimate the survival time and the Log-rank test was used to compare the survival time between groups of categorical variables. The multivariable survival regression model was used to identify a significant predictor of time to recovery among COVID-19 patients at a P value ⩽ 0.05 with a 95% CI. RESULT: In this study, 92% of patients admitted to Jimma University COVID-19 treatment center and Mettu Karl Comprehensive Specialized Hospital COVID-19 treatment center were recovered from COVID-19 after a maximum of 33 days of follow-up. The overall incidence density was 11.99/100 PD (person day) with a 95% CI of [11.273, 12.719] per 100 PD after a total of 3452 PD observations. The median time of recovery from COVID-19 was 10 days. Age (AHR = 1.945, 95% CI: 1.157, 3.268), hypertension (AHR = 1.856, 95% CI, 1.30, 2.63), diabetes (AHR = 1.406, 95% CI, 1.05, 1.84), being critical (0.298, 2039, 0.434), cancer (AHR = 3.050, 95% CI, 1.172, 7.943), and tuberculosis (AHR = 2.487, 95% CI, 1.504, 4.110) were found to be independent predictors of time to recovery of COVID-19 patients. CONCLUSION: A total of 92% of patients were recovered within 10 days of the median time. Age, hypertension, diabetes mellitus, tuberculosis, severity of the case, cancer, and the presence of acute kidney injury were predictors of recovery time of COVID-19 patients. Therefore, healthcare providers should give strict follow-up and priority to elderly patients with chronic illnesses and those under supportive care. Elsevier 2022-11-17 /pmc/articles/PMC9673091/ /pubmed/36415676 http://dx.doi.org/10.1016/j.amsu.2022.104917 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Cohort Study
Tsegaye, Serkalem
Bekele, Firomsa
Lulu, Yohanes
Debele, Gebiso Roba
Bekana, Teshome
Tolesa, Leta Deressa
Bidira, Kebebe
Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title_full Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title_fullStr Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title_full_unstemmed Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title_short Time to recovery and its predictors among COVID-19 positive patients admitted to treatment centers of Southwestern Ethiopian hospitals. A multicenter retrospective cohort study
title_sort time to recovery and its predictors among covid-19 positive patients admitted to treatment centers of southwestern ethiopian hospitals. a multicenter retrospective cohort study
topic Cohort Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673091/
https://www.ncbi.nlm.nih.gov/pubmed/36415676
http://dx.doi.org/10.1016/j.amsu.2022.104917
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