Cargando…

Murine model of triosephosphate isomerase deficiency with anemia and severe neuromuscular dysfunction

Triosephosphate isomerase deficiency (TPI Df) is a rare, aggressive genetic disease that typically affects young children and currently has no established treatment. TPI Df is characterized by hemolytic anemia, progressive neuromuscular degeneration, and a markedly reduced lifespan. The disease has...

Descripción completa

Detalles Bibliográficos
Autores principales:	Myers, Tracey D., Ferguson, Carolyn, Gliniak, Eric, Homanics, Gregg E., Palladino, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673098/ https://www.ncbi.nlm.nih.gov/pubmed/36405628 http://dx.doi.org/10.1016/j.crneur.2022.100062

Ejemplares similares

Newly discovered roles of triosephosphate isomerase including functions within the nucleus
por: Myers, Tracey D., et al.
Publicado: (2023)

Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency
por: VanDemark, Andrew P., et al.
Publicado: (2022)

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics
por: Roland, Bartholomew P., et al.
Publicado: (2016)

Triosephosphate-Isomerase Deficiency: Epiphenomenon or Cause of Loin Pain Haematuria Syndrome?
por: Schurek, Hans-Joachim, et al.
Publicado: (2022)

Structure of triosephosphate isomerase from Cryptosporidium parvum
por: Nguyen, Trang N., et al.
Publicado: (2011)

Identification of fibrillogenic regions in human triosephosphate isomerase
por: Carcamo-Noriega, Edson N., et al.
Publicado: (2016)

Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency
por: Segal, Joanna, et al.
Publicado: (2019)

Autoantibodies against triosephosphate isomerase. A possible clue to pathogenesis of hemolytic anemia in infectious mononucleosis
Publicado: (1990)

Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis
por: Grüning, Nana-Maria, et al.
Publicado: (2014)

Triosephosphate isomerase: the perfect enzyme, but how does it work?
por: Helliwell, John R.
Publicado: (2021)

Triosephosphate Isomerase Deficiency: E105D Mutation in Unrelated Patients and Review of the Literature
por: Selamioğlu, Arzu, et al.
Publicado: (2023)

Role of Loop-Clamping Side Chains in Catalysis by Triosephosphate Isomerase
por: Zhai, Xiang, et al.
Publicado: (2015)

Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini
por: Son, Jonghyeon, et al.
Publicado: (2018)

Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target
por: Enríquez-Flores, Sergio, et al.
Publicado: (2020)

Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity
por: Ferraro, Florencia, et al.
Publicado: (2020)

Perturbation of the Dimer Interface of Triosephosphate Isomerase and its Effect on Trypanosoma cruzi
por: Olivares-Illana, Vanesa, et al.
Publicado: (2007)

Triosephosphate Isomerase Gene Characterization and Potential Zoonotic Transmission of Giardia duodenalis
por: Sulaiman, Irshad M., et al.
Publicado: (2003)

A Novel Inhibitor of Mammalian Triosephosphate Isomerase Found by an In Silico Approach
por: Marsh, Lorraine, et al.
Publicado: (2014)

Male Mice Express Spermatogenic Cell-Specific Triosephosphate Isomerase Isozymes
por: Ijiri, Takashi W, et al.
Publicado: (2013)

Complex kinetics and residual structure in the thermal unfolding of yeast triosephosphate isomerase
por: Labastida-Polito, Ariana, et al.
Publicado: (2015)

Novel and Selective Rhipicephalus microplus Triosephosphate Isomerase Inhibitors with Acaricidal Activity
por: Saramago, Luiz, et al.
Publicado: (2018)

Clinical significance and prognostic value of Triosephosphate isomerase expression in gastric cancer
por: Chen, Tingting, et al.
Publicado: (2017)

Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection
por: Trujillo, Carolina, et al.
Publicado: (2014)

Structural Effects of Protein Aging: Terminal Marking by Deamidation in Human Triosephosphate Isomerase
por: de la Mora-de la Mora, Ignacio, et al.
Publicado: (2015)

Population expansion and gene flow in Giardia duodenalis as revealed by triosephosphate isomerase gene
por: Choy, Seow Huey, et al.
Publicado: (2015)

Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum
por: Park, Sang Ho, et al.
Publicado: (2015)

Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomes
por: Rodríguez-Bolaños, Monica, et al.
Publicado: (2016)

Disulfiram as a novel inactivator of Giardia lamblia triosephosphate isomerase with antigiardial potential
por: Castillo-Villanueva, Adriana, et al.
Publicado: (2017)

Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase
por: Kulkarni, Yashraj S., et al.
Publicado: (2017)

Native aggregation is a common feature among triosephosphate isomerases of different species
por: Rodríguez-Bolaños, Mónica, et al.
Publicado: (2020)

Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase
por: García-Torres, Itzhel, et al.
Publicado: (2023)

Effects of a Buried Cysteine-To-Serine Mutation on Yeast Triosephosphate Isomerase Structure and Stability
por: Hernández-Santoyo, Alejandra, et al.
Publicado: (2012)

Molecular epidemiology of giardiasis among Orang Asli in Malaysia: application of the triosephosphate isomerase gene
por: Anuar, Tengku Shahrul, et al.
Publicado: (2014)

Enzyme Architecture: The Effect of Replacement and Deletion Mutations of Loop 6 on Catalysis by Triosephosphate Isomerase
por: Zhai, Xiang, et al.
Publicado: (2014)

Substrate-Induced Dimerization of Engineered Monomeric Variants of Triosephosphate Isomerase from Trichomonas vaginalis
por: Lara-Gonzalez, Samuel, et al.
Publicado: (2015)

Structural Basis for Redox Regulation of Cytoplasmic and Chloroplastic Triosephosphate Isomerases from Arabidopsis thaliana
por: López-Castillo, Laura M., et al.
Publicado: (2016)

Correction to ‘Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomes’
por: Rodríguez-Bolaños, Monica, et al.
Publicado: (2016)

Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment
por: Aguilera, Elena, et al.
Publicado: (2018)

Cytosolic Triosephosphate Isomerase from Arabidopsis thaliana Is Reversibly Modified by Glutathione on Cysteines 127 and 218
por: Dumont, Sébastien, et al.
Publicado: (2016)

Species-Specific Inactivation of Triosephosphate Isomerase from Trypanosoma brucei: Kinetic and Molecular Dynamics Studies
por: Vázquez-Raygoza, Alejandra, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_32v4nvpr0ns8uk5kov6ioo07u6