Synthesis and Structure–Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494

[Image: see text] In the hunt for new antibiotics with activity against Gram-negative pathogens, the outer membrane β-barrel assembly machine (BAM) complex has become an increasingly interesting target. The recently reported BAM complex inhibitor, MRL-494, was discovered via a screening campaign for...

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Detalles Bibliográficos
Autores principales: Wade, Nicola, Wesseling, Charlotte M. J., Innocenti, Paolo, Slingerland, Cornelis J., Koningstein, Gregory M., Luirink, Joen, Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673140/
https://www.ncbi.nlm.nih.gov/pubmed/36318734
http://dx.doi.org/10.1021/acsinfecdis.2c00459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673140/
https://www.ncbi.nlm.nih.gov/pubmed/36318734
http://dx.doi.org/10.1021/acsinfecdis.2c00459

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