Impact of parasite genomic dynamics on the sensitivity of Plasmodium falciparum isolates to piperaquine and other antimalarial drugs

BACKGROUND: Dihydroartemisinin-piperaquine (DHA-PPQ) is an alternative first-line antimalarial to artemether-lumefantrine in Kenya. However, recent reports on the emergence of PPQ resistance in Southeast Asia threaten its continued use in Kenya and Africa. In line with the policy on continued deploy...

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Detalles Bibliográficos
Autores principales: Wakoli, Dancan M., Ondigo, Bartholomew N., Ochora, Douglas O., Amwoma, Joseph G., Okore, Winnie, Mwakio, Edwin W., Chemwor, Gladys, Juma, Jackeline, Okoth, Raphael, Okudo, Charles, Yeda, Redemptah, Opot, Benjamin H., Cheruiyot, Agnes C., Juma, Dennis, Roth, Amanda, Ogutu, Benhards R., Boudreaux, Daniel, Andagalu, Ben, Akala, Hoseah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673313/
https://www.ncbi.nlm.nih.gov/pubmed/36397090
http://dx.doi.org/10.1186/s12916-022-02652-2

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