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SIGIRR deficiency contributes to CD4 T cell abnormalities by facilitating the IL1/C/EBPβ/TNF-α signaling axis in rheumatoid arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a complex autoimmune disease with multiple etiological factors, among which aberrant memory CD4 T cells activation plays a key role in the initiation and perpetuation of the disease. SIGIRR (single immunoglobulin IL-1R-related receptor), a member of the IL-1...

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Detalles Bibliográficos
Autores principales:	Teng, Xiu, Mou, Da-Chao, Li, Hui-Fang, Jiao, Ling, Wu, Sha-Sha, Pi, Jin-Kui, Wang, Yan, Zhu, Meng-Li, Tang, Meng, Liu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673409/ https://www.ncbi.nlm.nih.gov/pubmed/36401167 http://dx.doi.org/10.1186/s10020-022-00563-9

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