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Brain tumour segmentation based on an improved U-Net

BACKGROUND: Automatic segmentation of brain tumours using deep learning algorithms is currently one of the research hotspots in the medical image segmentation field. An improved U-Net network is proposed to segment brain tumours to improve the segmentation effect of brain tumours. METHODS: To solve...

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Autores principales: Zheng, Ping, Zhu, Xunfei, Guo, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673428/
https://www.ncbi.nlm.nih.gov/pubmed/36401207
http://dx.doi.org/10.1186/s12880-022-00931-1
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author Zheng, Ping
Zhu, Xunfei
Guo, Wenbo
author_facet Zheng, Ping
Zhu, Xunfei
Guo, Wenbo
author_sort Zheng, Ping
collection PubMed
description BACKGROUND: Automatic segmentation of brain tumours using deep learning algorithms is currently one of the research hotspots in the medical image segmentation field. An improved U-Net network is proposed to segment brain tumours to improve the segmentation effect of brain tumours. METHODS: To solve the problems of other brain tumour segmentation models such as U-Net, including insufficient ability to segment edge details and reuse feature information, poor extraction of location information and the commonly used binary cross-entropy and Dice loss are often ineffective when used as loss functions for brain tumour segmentation models, we propose a serial encoding–decoding structure, which achieves improved segmentation performance by adding hybrid dilated convolution (HDC) modules and concatenation between each module of two serial networks. In addition, we propose a new loss function to focus the model more on samples that are difficult to segment and classify. We compared the results of our proposed model and the commonly used segmentation models under the IOU, PA, Dice, precision, Hausdorf95, and ASD metrics. RESULTS: The performance of the proposed method outperforms other segmentation models in each metric. In addition, the schematic diagram of the segmentation results shows that the segmentation results of our algorithm are closer to the ground truth, showing more brain tumour details, while the segmentation results of other algorithms are smoother. CONCLUSIONS: Our algorithm has better semantic segmentation performance than other commonly used segmentation algorithms. The technology we propose can be used in the brain tumour diagnosis to provide better protection for patients' later treatments.
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spelling pubmed-96734282022-11-19 Brain tumour segmentation based on an improved U-Net Zheng, Ping Zhu, Xunfei Guo, Wenbo BMC Med Imaging Research BACKGROUND: Automatic segmentation of brain tumours using deep learning algorithms is currently one of the research hotspots in the medical image segmentation field. An improved U-Net network is proposed to segment brain tumours to improve the segmentation effect of brain tumours. METHODS: To solve the problems of other brain tumour segmentation models such as U-Net, including insufficient ability to segment edge details and reuse feature information, poor extraction of location information and the commonly used binary cross-entropy and Dice loss are often ineffective when used as loss functions for brain tumour segmentation models, we propose a serial encoding–decoding structure, which achieves improved segmentation performance by adding hybrid dilated convolution (HDC) modules and concatenation between each module of two serial networks. In addition, we propose a new loss function to focus the model more on samples that are difficult to segment and classify. We compared the results of our proposed model and the commonly used segmentation models under the IOU, PA, Dice, precision, Hausdorf95, and ASD metrics. RESULTS: The performance of the proposed method outperforms other segmentation models in each metric. In addition, the schematic diagram of the segmentation results shows that the segmentation results of our algorithm are closer to the ground truth, showing more brain tumour details, while the segmentation results of other algorithms are smoother. CONCLUSIONS: Our algorithm has better semantic segmentation performance than other commonly used segmentation algorithms. The technology we propose can be used in the brain tumour diagnosis to provide better protection for patients' later treatments. BioMed Central 2022-11-18 /pmc/articles/PMC9673428/ /pubmed/36401207 http://dx.doi.org/10.1186/s12880-022-00931-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Zheng, Ping
Zhu, Xunfei
Guo, Wenbo
Brain tumour segmentation based on an improved U-Net
title Brain tumour segmentation based on an improved U-Net
title_full Brain tumour segmentation based on an improved U-Net
title_fullStr Brain tumour segmentation based on an improved U-Net
title_full_unstemmed Brain tumour segmentation based on an improved U-Net
title_short Brain tumour segmentation based on an improved U-Net
title_sort brain tumour segmentation based on an improved u-net
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673428/
https://www.ncbi.nlm.nih.gov/pubmed/36401207
http://dx.doi.org/10.1186/s12880-022-00931-1
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