Cargando…

Pain in critically ill COVID-19 patients: An Italian retrospective study

We retrospectively analyzed the data from patients admitted to the intensive care unit (ICU) of the Hospital of L’Aquila during the first and second waves of pandemic to identify pain related to COVID-19. Pain was evaluated by using the Numerical Rating Scale, and the assessment for neuropathic dist...

Descripción completa

Detalles Bibliográficos
Autores principales: Petrucci, Emiliano, Cofini, Vincenza, Pizzi, Barbara, Cascella, Marco, Marrocco, Gioele, Ceccaroni, Gianmaria, Necozione, Stefano, Vittori, Alessandro, Marinangeli, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673487/
https://www.ncbi.nlm.nih.gov/pubmed/36447524
http://dx.doi.org/10.1515/med-2022-0600
_version_ 1784832951191601152
author Petrucci, Emiliano
Cofini, Vincenza
Pizzi, Barbara
Cascella, Marco
Marrocco, Gioele
Ceccaroni, Gianmaria
Necozione, Stefano
Vittori, Alessandro
Marinangeli, Franco
author_facet Petrucci, Emiliano
Cofini, Vincenza
Pizzi, Barbara
Cascella, Marco
Marrocco, Gioele
Ceccaroni, Gianmaria
Necozione, Stefano
Vittori, Alessandro
Marinangeli, Franco
author_sort Petrucci, Emiliano
collection PubMed
description We retrospectively analyzed the data from patients admitted to the intensive care unit (ICU) of the Hospital of L’Aquila during the first and second waves of pandemic to identify pain related to COVID-19. Pain was evaluated by using the Numerical Rating Scale, and the assessment for neuropathic disturbances of pain was performed with von Frey’s hair and Lindblom tests. Pain increased significantly during hospitalization (from 48% at hospital admission to 94.3% at ICU discharge). Female patients were affected by somatic pain in 32.8% of the cases and by somatic pain and pain with neuropathic features (NFs) in 23.5% of the cases, during the ICU stay. Somatic pain and pain with NFs affected more frequently patients with cardiological and respiratory comorbidities. Patients treated with continuous positive airway pressure via helmet had a higher frequency of somatic pain and pain with neuropathic disturbances (84 and 74%, respectively). The frequency of somatic pain and pain with neuropathic disturbances was lower in patients sedated with propofol combined with ketamine. Females have been associated with a higher risk of somatic pain and pain with NFs. Patients with cardiological and respiratory comorbidities undergoing noninvasive ventilation had higher levels of pain. As conclusion, ketamine may reduce the promotion or the worsening of pain in COVID-19 patients.
format Online
Article
Text
id pubmed-9673487
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher De Gruyter
record_format MEDLINE/PubMed
spelling pubmed-96734872022-11-28 Pain in critically ill COVID-19 patients: An Italian retrospective study Petrucci, Emiliano Cofini, Vincenza Pizzi, Barbara Cascella, Marco Marrocco, Gioele Ceccaroni, Gianmaria Necozione, Stefano Vittori, Alessandro Marinangeli, Franco Open Med (Wars) Research Article We retrospectively analyzed the data from patients admitted to the intensive care unit (ICU) of the Hospital of L’Aquila during the first and second waves of pandemic to identify pain related to COVID-19. Pain was evaluated by using the Numerical Rating Scale, and the assessment for neuropathic disturbances of pain was performed with von Frey’s hair and Lindblom tests. Pain increased significantly during hospitalization (from 48% at hospital admission to 94.3% at ICU discharge). Female patients were affected by somatic pain in 32.8% of the cases and by somatic pain and pain with neuropathic features (NFs) in 23.5% of the cases, during the ICU stay. Somatic pain and pain with NFs affected more frequently patients with cardiological and respiratory comorbidities. Patients treated with continuous positive airway pressure via helmet had a higher frequency of somatic pain and pain with neuropathic disturbances (84 and 74%, respectively). The frequency of somatic pain and pain with neuropathic disturbances was lower in patients sedated with propofol combined with ketamine. Females have been associated with a higher risk of somatic pain and pain with NFs. Patients with cardiological and respiratory comorbidities undergoing noninvasive ventilation had higher levels of pain. As conclusion, ketamine may reduce the promotion or the worsening of pain in COVID-19 patients. De Gruyter 2022-11-17 /pmc/articles/PMC9673487/ /pubmed/36447524 http://dx.doi.org/10.1515/med-2022-0600 Text en © 2022 the author(s), published by De Gruyter https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Research Article
Petrucci, Emiliano
Cofini, Vincenza
Pizzi, Barbara
Cascella, Marco
Marrocco, Gioele
Ceccaroni, Gianmaria
Necozione, Stefano
Vittori, Alessandro
Marinangeli, Franco
Pain in critically ill COVID-19 patients: An Italian retrospective study
title Pain in critically ill COVID-19 patients: An Italian retrospective study
title_full Pain in critically ill COVID-19 patients: An Italian retrospective study
title_fullStr Pain in critically ill COVID-19 patients: An Italian retrospective study
title_full_unstemmed Pain in critically ill COVID-19 patients: An Italian retrospective study
title_short Pain in critically ill COVID-19 patients: An Italian retrospective study
title_sort pain in critically ill covid-19 patients: an italian retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673487/
https://www.ncbi.nlm.nih.gov/pubmed/36447524
http://dx.doi.org/10.1515/med-2022-0600
work_keys_str_mv AT petrucciemiliano painincriticallyillcovid19patientsanitalianretrospectivestudy
AT cofinivincenza painincriticallyillcovid19patientsanitalianretrospectivestudy
AT pizzibarbara painincriticallyillcovid19patientsanitalianretrospectivestudy
AT cascellamarco painincriticallyillcovid19patientsanitalianretrospectivestudy
AT marroccogioele painincriticallyillcovid19patientsanitalianretrospectivestudy
AT ceccaronigianmaria painincriticallyillcovid19patientsanitalianretrospectivestudy
AT necozionestefano painincriticallyillcovid19patientsanitalianretrospectivestudy
AT vittorialessandro painincriticallyillcovid19patientsanitalianretrospectivestudy
AT marinangelifranco painincriticallyillcovid19patientsanitalianretrospectivestudy