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Central Nervous System Actions of Leptin Improve Cardiac Function After Ischemia–Reperfusion: Roles of Sympathetic Innervation and Sex Differences
BACKGROUND: Therapeutic strategies for preventing paradoxical reperfusion injury after myocardial ischemia are limited. We tested whether central nervous system actions of leptin induce important protective effects on cardiac function and metabolism after myocardial ischemia/reperfusion (I/R) injury...
Autores principales: | Omoto, Ana C. M., do Carmo, Jussara M., Nelson, Benjamin, Aitken, Nikaela, Dai, Xuemei, Moak, Sydney, Flynn, Elizabeth, Wang, Zhen, Mouton, Alan J., Li, Xuan, Hall, John E., da Silva, Alexandre A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673649/ https://www.ncbi.nlm.nih.gov/pubmed/36300667 http://dx.doi.org/10.1161/JAHA.122.027081 |
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