Cargando…

Inhaled Carbon Dioxide Improves Neurological Outcomes by Downregulating Hippocampal Autophagy and Apoptosis in an Asphyxia‐Induced Cardiac Arrest and Resuscitation Rat Model

BACKGROUND: Protracted cerebral hypoperfusion following cardiac arrest (CA) may cause poor neurological recovery. We hypothesized that inhaled carbon dioxide (CO(2)) could augment cerebral blood flow (CBF) and improve post‐CA neurological outcomes. METHODS AND RESULTS: After 6‐minute asphyxia‐induce...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chih‐Hung, Huang, Chien‐Hua, Tsai, Min‐Shan, Wang, Chan‐Chi, Chang, Wei‐Tien, Liu, Shing‐Hwa, Chen, Wen‐Jone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673650/
https://www.ncbi.nlm.nih.gov/pubmed/36314493
http://dx.doi.org/10.1161/JAHA.122.027685