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Inhaled Carbon Dioxide Improves Neurological Outcomes by Downregulating Hippocampal Autophagy and Apoptosis in an Asphyxia‐Induced Cardiac Arrest and Resuscitation Rat Model
BACKGROUND: Protracted cerebral hypoperfusion following cardiac arrest (CA) may cause poor neurological recovery. We hypothesized that inhaled carbon dioxide (CO(2)) could augment cerebral blood flow (CBF) and improve post‐CA neurological outcomes. METHODS AND RESULTS: After 6‐minute asphyxia‐induce...
Autores principales: | Wang, Chih‐Hung, Huang, Chien‐Hua, Tsai, Min‐Shan, Wang, Chan‐Chi, Chang, Wei‐Tien, Liu, Shing‐Hwa, Chen, Wen‐Jone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673650/ https://www.ncbi.nlm.nih.gov/pubmed/36314493 http://dx.doi.org/10.1161/JAHA.122.027685 |
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