Senescent-like Blood Lymphocytes and Disease Progression in Amyotrophic Lateral Sclerosis

BACKGROUND AND OBJECTIVES: Aging is known to exacerbate neuroinflammation, and in the neurodegenerative disorder amyotrophic lateral sclerosis (ALS), an older age is associated with a worse prognosis. We have previously shown the activation of cell senescence pathways in the proteome of peripheral b...

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Detalles Bibliográficos
Autores principales: Yildiz, Ozlem, Schroth, Johannes, Tree, Timothy, Turner, Martin R., Shaw, Pamela J., Henson, Sian M., Malaspina, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673751/
https://www.ncbi.nlm.nih.gov/pubmed/36323511
http://dx.doi.org/10.1212/NXI.0000000000200042

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