Threshold condition and non pharmaceutical interventions’s control strategies for elimination of COVID-19

In this work we focus on the eradication of the COVID-19 infection with the help of almost Non Pharmaceutical Interventions(NPIs), using mathematical modelling. First the basic reproduction number [Formula: see text] is investigated. Then, on the basis of sensitivity test of [Formula: see text] , th...

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Detalles Bibliográficos
Autores principales: Zamir, Muhammad, Nadeem, Fawad, Abdeljawad, Thabet, Hammouch, Zakia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673771/
https://www.ncbi.nlm.nih.gov/pubmed/36466743
http://dx.doi.org/10.1016/j.rinp.2020.103698
Descripción
Sumario:In this work we focus on the eradication of the COVID-19 infection with the help of almost Non Pharmaceutical Interventions(NPIs), using mathematical modelling. First the basic reproduction number [Formula: see text] is investigated. Then, on the basis of sensitivity test of [Formula: see text] , the most active/sensitive parameters are presented in detail. Non Pharmaceutical Interventions(NPIs) are applied to control the sensitive parameters. The major NPIs are, stay home (isolation), sanitizers (wash hands), Treatment of side effects of infection, like throat infection etc and face mask. These NPIs helps in mitigation and reducing the size of outbreak of the disease. Threshold condition for global stability of the disease free state is investigated.The NPI’s are used in different ratios to formulate a strategy. The results of these strategies are validated using Matlab software.

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