Cargando…

1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases

A series of 1,2,3-benzoxathiazine-2,2-dioxides possessing various substituents in the 5, 7, or 8 position was obtained from corresponding 2-hydroxybenzaldehydes in their reaction with sulfamoyl chloride. 5-, 7-, and 8-aryl substituted 1,2,3-benzoxathiazine-2,2-dioxides were prepared from aryl substi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ivanova, Jekaterina, Abdoli, Morteza, Nocentini, Alessio, Žalubovskis, Raivis, Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673787/ https://www.ncbi.nlm.nih.gov/pubmed/36373195 http://dx.doi.org/10.1080/14756366.2022.2142787

Ejemplares similares

Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II
por: Ivanova, Jekaterīna, et al.
Publicado: (2023)

Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2019)

7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2020)

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2023)

3H-1,2-Benzoxaphosphepine 2-oxides as selective inhibitors of carbonic anhydrase IX and XII
por: Pustenko, Aleksandrs, et al.
Publicado: (2022)

Investigation of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates as carbonic anhydrase inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2023)

4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

Novel thiazolone-benzenesulphonamide inhibitors of human and bacterial carbonic anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2023)

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII
por: Balašova, Anastasija, et al.
Publicado: (2023)

3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2017)

Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2022)

The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2020)

Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides
por: Abdoli, Morteza, et al.
Publicado: (2023)

Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors
por: De Simone, Giuseppina, et al.
Publicado: (2014)

Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
por: Nocentini, Alessio, et al.
Publicado: (2021)

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
por: Angeli, Andrea, et al.
Publicado: (2020)

An overview on the recently discovered iota-carbonic anhydrases
por: Nocentini, Alessio, et al.
Publicado: (2021)

Carbonic Anhydrase Inhibitors as Novel Antibacterials in the Era of Antibiotic Resistance: Where Are We Now?
por: Nocentini, Alessio, et al.
Publicado: (2023)

Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2018)

Bacterial ι-carbonic anhydrase: a new active class of carbonic anhydrase identified in the genome of the Gram-negative bacterium Burkholderia territorii
por: Del Prete, Sonia, et al.
Publicado: (2020)

Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes
por: Zoppi, Carlotta, et al.
Publicado: (2020)

Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII
por: Giovannuzzi, Simone, et al.
Publicado: (2022)

Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors
por: Giovannuzzi, Simone, et al.
Publicado: (2023)

Role of Carbonic Anhydrase in Cerebral Ischemia and Carbonic Anhydrase Inhibitors as Putative Protective Agents
por: Bulli, Irene, et al.
Publicado: (2021)

Coumarins effectively inhibit bacterial α-carbonic anhydrases
por: Giovannuzzi, Simone, et al.
Publicado: (2022)

Coumarins inhibit η-class carbonic anhydrase from Plasmodium falciparum
por: Giovannuzzi, Simone, et al.
Publicado: (2022)

5-(Sulfamoyl)thien-2-yl 1,3-oxazole inhibitors of carbonic anhydrase II with hydrophilic periphery
por: Kalinin, Stanislav, et al.
Publicado: (2022)

Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae
por: Nocentini, Alessio, et al.
Publicado: (2021)

Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles
por: Nocentini, Alessio, et al.
Publicado: (2017)

Inhibition studies of bacterial α-carbonic anhydrases with phenols
por: Giovannuzzi, Simone, et al.
Publicado: (2022)

Phaeodactylum tricornutum as a model organism for testing the membrane penetrability of sulphonamide carbonic anhydrase inhibitors
por: Rogato, Alessandra, et al.
Publicado: (2019)

Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators
por: Nocentini, Alessio, et al.
Publicado: (2020)

Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms
por: Nocentini, Alessio, et al.
Publicado: (2018)

Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides
por: Angeli, Andrea, et al.
Publicado: (2023)

Carbonic Anhydrases and Metabolism
por: Supuran, Claudiu T.
Publicado: (2018)

Intracellular Binding/Unbinding Kinetics of Approved Drugs to Carbonic Anhydrase II Observed by in-Cell NMR
por: Luchinat, Enrico, et al.
Publicado: (2020)

Activation of carbonic anhydrase isoforms involved in modulation of emotional memory and cognitive disorders with histamine agonists, antagonists and derivatives
por: Provensi, Gustavo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b9lc594lu1cv92ktd7no84m7t1