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A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation

Takayasu’s arteritis is a chronic inflammation of the large arteries such as the aorta and its primary branches, causing progressive arterial occlusion. This leads to reduced blood flow in the limbs and organs, resulting in arm or leg claudication, diminished or absent peripheral pulses, and end-org...

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Autores principales: Memon, Tehsim, Shekha, Tufayl Ahmed M, Acharya, Pavan, Nishu, Rifath I, Akhter, Naila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673871/
https://www.ncbi.nlm.nih.gov/pubmed/36415359
http://dx.doi.org/10.7759/cureus.30472
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author Memon, Tehsim
Shekha, Tufayl Ahmed M
Acharya, Pavan
Nishu, Rifath I
Akhter, Naila
author_facet Memon, Tehsim
Shekha, Tufayl Ahmed M
Acharya, Pavan
Nishu, Rifath I
Akhter, Naila
author_sort Memon, Tehsim
collection PubMed
description Takayasu’s arteritis is a chronic inflammation of the large arteries such as the aorta and its primary branches, causing progressive arterial occlusion. This leads to reduced blood flow in the limbs and organs, resulting in arm or leg claudication, diminished or absent peripheral pulses, and end-organ ischemia. Stroke is one of the common complications; however, it is rarely the initial presentation. We describe one such case of a 16-year-old female, who presented with right-sided hemiparesis and non-fluent aphasia, without any significant past history. On examination, her right arm was cold and pulseless. She was extensively investigated for the cause of her presentation. Only non-specific inflammatory markers such as erythrocyte sedimentation rate (ESR) were elevated. Imaging studies revealed left middle cerebral artery territory infarct with occlusion of common carotid arteries, bilateral bifurcation, most parts of the left internal carotid artery, and the proximal part of the right internal carotid artery. She was diagnosed with Takayasu's arteritis and was prescribed steroids, on which she gradually recovered and was discharged. In conclusion, young patients, who present with stroke, should be investigated for Takayasu’s arteritis, which leads to earlier treatment and prevention of further life-threatening end-organ damage.
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spelling pubmed-96738712022-11-21 A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation Memon, Tehsim Shekha, Tufayl Ahmed M Acharya, Pavan Nishu, Rifath I Akhter, Naila Cureus Internal Medicine Takayasu’s arteritis is a chronic inflammation of the large arteries such as the aorta and its primary branches, causing progressive arterial occlusion. This leads to reduced blood flow in the limbs and organs, resulting in arm or leg claudication, diminished or absent peripheral pulses, and end-organ ischemia. Stroke is one of the common complications; however, it is rarely the initial presentation. We describe one such case of a 16-year-old female, who presented with right-sided hemiparesis and non-fluent aphasia, without any significant past history. On examination, her right arm was cold and pulseless. She was extensively investigated for the cause of her presentation. Only non-specific inflammatory markers such as erythrocyte sedimentation rate (ESR) were elevated. Imaging studies revealed left middle cerebral artery territory infarct with occlusion of common carotid arteries, bilateral bifurcation, most parts of the left internal carotid artery, and the proximal part of the right internal carotid artery. She was diagnosed with Takayasu's arteritis and was prescribed steroids, on which she gradually recovered and was discharged. In conclusion, young patients, who present with stroke, should be investigated for Takayasu’s arteritis, which leads to earlier treatment and prevention of further life-threatening end-organ damage. Cureus 2022-10-19 /pmc/articles/PMC9673871/ /pubmed/36415359 http://dx.doi.org/10.7759/cureus.30472 Text en Copyright © 2022, Memon et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Memon, Tehsim
Shekha, Tufayl Ahmed M
Acharya, Pavan
Nishu, Rifath I
Akhter, Naila
A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title_full A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title_fullStr A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title_full_unstemmed A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title_short A Case Report of Takayasu’s Arteritis With Cerebral Infarction As Initial Presentation
title_sort case report of takayasu’s arteritis with cerebral infarction as initial presentation
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673871/
https://www.ncbi.nlm.nih.gov/pubmed/36415359
http://dx.doi.org/10.7759/cureus.30472
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