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Clearance of therapeutic antibody glycoforms after subcutaneous and intravenous injection in a porcine model

A relatively low clearance is one of the prominent favorable features of immunoglobulin G1-based therapeutic monoclonal antibodies (mAbs). Various studies have observed differential clearance of mAb glycoforms, including oligomannose glycoforms, which are considered a critical quality attribute beca...

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Detalles Bibliográficos
Autores principales:	Falck, David, Lechmann, Martin, Momčilović, Ana, Thomann, Marco, Koeleman, Carolien A. M., Jany, Cordula, Malik, Sebastian, Wuhrer, Manfred, Reusch, Dietmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673920/ https://www.ncbi.nlm.nih.gov/pubmed/36383465 http://dx.doi.org/10.1080/19420862.2022.2145929

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