Early recruitment of PARP-dependent m(8)A RNA methylation at DNA lesions is subsequently accompanied by active DNA demethylation

RNA methylation, especially 6-methyladenosine (m(6)A)-modified RNAs, plays a specific role in DNA damage response (DDR). Here, we also observe that RNA modified at 8-methyladenosine (m(8)A) is recruited to UVA-damaged chromatin immediately after microirradiation. Interestingly, the level of m(8)A RN...

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Detalles Bibliográficos
Autores principales: Legartová, Soňa, Svobodová Kovaříková, Alena, Běhalová Suchánková, Jana, Polášek-Sedláčková, Hana, Bártová, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9673957/
https://www.ncbi.nlm.nih.gov/pubmed/36382943
http://dx.doi.org/10.1080/15476286.2022.2139109

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