wnt16 regulates spine and muscle morphogenesis through parallel signals from notochord and dermomyotome

Bone and muscle are coupled through developmental, mechanical, paracrine, and autocrine signals. Genetic variants at the CPED1-WNT16 locus are dually associated with bone- and muscle-related traits. While Wnt16 is necessary for bone mass and strength, this fails to explain pleiotropy at this locus....

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Detalles Bibliográficos
Autores principales: Watson, Claire J., Tang, W. Joyce, Rojas, Maria F., Fiedler, Imke A. K., Morfin Montes de Oca, Ernesto, Cronrath, Andrea R., Callies, Lulu K., Swearer, Avery Angell, Ahmed, Ali R., Sethuraman, Visali, Addish, Sumaya, Farr, Gist H., Gómez, Arianna Ericka, Rai, Jyoti, Monstad-Rios, Adrian T., Gardiner, Edith M., Karasik, David, Maves, Lisa, Busse, Bjorn, Hsu, Yi-Hsiang, Kwon, Ronald Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674140/
https://www.ncbi.nlm.nih.gov/pubmed/36346812
http://dx.doi.org/10.1371/journal.pgen.1010496

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