Spinal neuropeptide Y Y1 receptor-expressing neurons are a pharmacotherapeutic target for the alleviation of neuropathic pain

Peripheral nerve injury sensitizes a complex network of spinal cord dorsal horn (DH) neurons to produce allodynia and neuropathic pain. The identification of a druggable target within this network has remained elusive, but a promising candidate is the neuropeptide Y (NPY) Y1 receptor-expressing inte...

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Detalles Bibliográficos
Autores principales: Nelson, Tyler S., Sinha, Ghanshyam P., Santos, Diogo F. S., Jukkola, Peter, Prasoon, Pranav, Winter, Michelle K., McCarson, Ken E., Smith, Bret N., Taylor, Bradley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674229/
https://www.ncbi.nlm.nih.gov/pubmed/36343228
http://dx.doi.org/10.1073/pnas.2204515119

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