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CRISPR-based engineering of phages for in situ bacterial base editing

Investigation of microbial gene function is essential to the elucidation of ecological roles and complex genetic interactions that take place in microbial communities. While microbiome studies have increased in prevalence, the lack of viable in situ editing strategies impedes experimental progress,...

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Detalles Bibliográficos
Autores principales: Nethery, Matthew A., Hidalgo-Cantabrana, Claudio, Roberts, Avery, Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674246/
https://www.ncbi.nlm.nih.gov/pubmed/36343261
http://dx.doi.org/10.1073/pnas.2206744119