SLC7A8 is a key amino acids supplier for the metabolic programs that sustain homeostasis and activation of type 2 innate lymphoid cells

Group 2 innate lymphoid cells (ILC2) are innate counterparts of T helper 2 (Th2) cells that maintain tissue homeostasis and respond to injuries through rapid interleukin (IL)-5 and IL-13 secretion. ILC2s depend on availability of arginine and branched-chain amino acids for sustaining cellular fitnes...

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Detalles Bibliográficos
Autores principales: Panda, Santosh K., Kim, Do-Hyun, Desai, Pritesh, Rodrigues, Patrick F., Sudan, Raki, Gilfillan, Susan, Cella, Marina, Van Dyken, Steven J., Colonna, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674248/
https://www.ncbi.nlm.nih.gov/pubmed/36343258
http://dx.doi.org/10.1073/pnas.2215528119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674248/
https://www.ncbi.nlm.nih.gov/pubmed/36343258
http://dx.doi.org/10.1073/pnas.2215528119

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