Aβ and tau prions feature in the neuropathogenesis of Down syndrome

Down syndrome (DS) is caused by the triplication of chromosome 21 and is the most common chromosomal disorder in humans. Those individuals with DS who live beyond age 40 y develop a progressive dementia that is similar to Alzheimer’s disease (AD). Both DS and AD brains exhibit numerous extracellular...

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Detalles Bibliográficos
Autores principales: Condello, Carlo, Maxwell, Alison M., Castillo, Erika, Aoyagi, Atsushi, Graff, Caroline, Ingelsson, Martin, Lannfelt, Lars, Bird, Thomas D., Keene, C. Dirk, Seeley, William W., Perl, Daniel P., Head, Elizabeth, Prusiner, Stanley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674250/
https://www.ncbi.nlm.nih.gov/pubmed/36343257
http://dx.doi.org/10.1073/pnas.2212954119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674250/
https://www.ncbi.nlm.nih.gov/pubmed/36343257
http://dx.doi.org/10.1073/pnas.2212954119

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