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A retrospective study of COVID during pregnancy and the outcome of vaginal delivery

INTRODUCTION: SARS-CoV, MERS-CoV, and SARS-CoV-2, later named coronavirus disease 2019 (COVID-19), are three highly pathogenic and lethal human coronaviruses that have arisen in the last two decades. Pregnant women have a higher risk due to a special state of immunosuppression. However, there is no...

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Autores principales: Sunuwar, Neela, Jaishi, Prakash Poudel, Twayana, Anu Radha, Neupane, Prabhat Kiran, Neupane, Sandhya Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674396/
https://www.ncbi.nlm.nih.gov/pubmed/36438876
http://dx.doi.org/10.1016/j.amsu.2022.104880
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author Sunuwar, Neela
Jaishi, Prakash Poudel
Twayana, Anu Radha
Neupane, Prabhat Kiran
Neupane, Sandhya Kiran
author_facet Sunuwar, Neela
Jaishi, Prakash Poudel
Twayana, Anu Radha
Neupane, Prabhat Kiran
Neupane, Sandhya Kiran
author_sort Sunuwar, Neela
collection PubMed
description INTRODUCTION: SARS-CoV, MERS-CoV, and SARS-CoV-2, later named coronavirus disease 2019 (COVID-19), are three highly pathogenic and lethal human coronaviruses that have arisen in the last two decades. Pregnant women have a higher risk due to a special state of immunosuppression. However, there is no proof that pregnant women and their babies are more vulnerable to infection, as data is limited.The primary goal of this retrospective study is to examine the effects of early COVID-19 diagnosis and to address the best method of delivery based on medical records of neonatal and maternal outcomes observed at Nepal's Paropakar Maternity Hospital. This retrospective research will determine whether vaginal delivery is healthy compared to cesarean delivery and whether the outcome of a COVID-19 pregnancy in both mother and the baby is independent of the disease's status of the mother. METHODS: Study design: The proposed study is a retrospective cross-sectional study. PATIENTS POPULATION: 104 cases of COVID positive pregnancy with vaginal delivery or caesarean section. RESULTS: The neonatal outcomes of COVID pregnancy revealed at least 51% baby born with Low APGAR score, 18% born prematurely, 19% with low birth weight, 7% requiring NICU admission, 3% Neonatal asphyxia, and 2% Neonatal death. Furthermore, when normal vaginal delivery and Cesarean section were compared there was no significant between the differences found in the outcomes CONCLUSION: The COVID positive status had no association with the perinatal outcomes. Moreover, COVID status rarely affected the course of pregnancy. GUIDELINE: STROCSS 2021.
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spelling pubmed-96743962022-11-21 A retrospective study of COVID during pregnancy and the outcome of vaginal delivery Sunuwar, Neela Jaishi, Prakash Poudel Twayana, Anu Radha Neupane, Prabhat Kiran Neupane, Sandhya Kiran Ann Med Surg (Lond) Cross-sectional Study INTRODUCTION: SARS-CoV, MERS-CoV, and SARS-CoV-2, later named coronavirus disease 2019 (COVID-19), are three highly pathogenic and lethal human coronaviruses that have arisen in the last two decades. Pregnant women have a higher risk due to a special state of immunosuppression. However, there is no proof that pregnant women and their babies are more vulnerable to infection, as data is limited.The primary goal of this retrospective study is to examine the effects of early COVID-19 diagnosis and to address the best method of delivery based on medical records of neonatal and maternal outcomes observed at Nepal's Paropakar Maternity Hospital. This retrospective research will determine whether vaginal delivery is healthy compared to cesarean delivery and whether the outcome of a COVID-19 pregnancy in both mother and the baby is independent of the disease's status of the mother. METHODS: Study design: The proposed study is a retrospective cross-sectional study. PATIENTS POPULATION: 104 cases of COVID positive pregnancy with vaginal delivery or caesarean section. RESULTS: The neonatal outcomes of COVID pregnancy revealed at least 51% baby born with Low APGAR score, 18% born prematurely, 19% with low birth weight, 7% requiring NICU admission, 3% Neonatal asphyxia, and 2% Neonatal death. Furthermore, when normal vaginal delivery and Cesarean section were compared there was no significant between the differences found in the outcomes CONCLUSION: The COVID positive status had no association with the perinatal outcomes. Moreover, COVID status rarely affected the course of pregnancy. GUIDELINE: STROCSS 2021. Elsevier 2022-11-19 /pmc/articles/PMC9674396/ /pubmed/36438876 http://dx.doi.org/10.1016/j.amsu.2022.104880 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Cross-sectional Study
Sunuwar, Neela
Jaishi, Prakash Poudel
Twayana, Anu Radha
Neupane, Prabhat Kiran
Neupane, Sandhya Kiran
A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title_full A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title_fullStr A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title_full_unstemmed A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title_short A retrospective study of COVID during pregnancy and the outcome of vaginal delivery
title_sort retrospective study of covid during pregnancy and the outcome of vaginal delivery
topic Cross-sectional Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674396/
https://www.ncbi.nlm.nih.gov/pubmed/36438876
http://dx.doi.org/10.1016/j.amsu.2022.104880
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