Development of an extensive workflow for comprehensive clinical pharmacogenomic profiling: lessons from a pilot study on 100 whole exome sequencing data

This pilot study is aimed at implementing an approach for comprehensive clinical pharmacogenomics (PGx) profiling. Fifty patients with cardiovascular diseases and 50 healthy individuals underwent whole-exome sequencing. Data on 1800 PGx genes were extracted and analyzed through deep filtration separ...

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Detalles Bibliográficos
Autores principales: Tafazoli, Alireza, van der Lee, Maaike, Swen, Jesse J., Zeller, Anna, Wawrusiewicz-Kurylonek, Natalia, Mei, Hailiang, Vorderman, Ruben H. P., Konopko, Krzysztof, Zankiewicz, Andrzej, Miltyk, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674517/
https://www.ncbi.nlm.nih.gov/pubmed/35963939
http://dx.doi.org/10.1038/s41397-022-00286-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674517/
https://www.ncbi.nlm.nih.gov/pubmed/35963939
http://dx.doi.org/10.1038/s41397-022-00286-4

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