Acute dapsone poisoning with methemoglobinemia: a case report

Methemoglobinemia is a common complication of dapsone poisoning. Its´ treatment usually relies on methylene blue infusion. The aim of this study was to report a case of an acute dapsone poisoning with methemoglobinemia treated only with ascorbic acid and activated charcoal. A 16-year-old female volu...

Descripción completa

Detalles Bibliográficos
Autores principales: El Hamzaoui, Hamza, Chajai, Idriss, El Ouazzani, Mohamed Chahidi, Benhalima, Abdelkader, El Arfaoui, Manal, Alilou, Mustapha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674526/
https://www.ncbi.nlm.nih.gov/pubmed/36451721
http://dx.doi.org/10.11604/pamj.2022.43.20.34069
_version_ 1784833173729837056
author El Hamzaoui, Hamza
Chajai, Idriss
El Ouazzani, Mohamed Chahidi
Benhalima, Abdelkader
El Arfaoui, Manal
Alilou, Mustapha
author_facet El Hamzaoui, Hamza
Chajai, Idriss
El Ouazzani, Mohamed Chahidi
Benhalima, Abdelkader
El Arfaoui, Manal
Alilou, Mustapha
author_sort El Hamzaoui, Hamza
collection PubMed
description Methemoglobinemia is a common complication of dapsone poisoning. Its´ treatment usually relies on methylene blue infusion. The aim of this study was to report a case of an acute dapsone poisoning with methemoglobinemia treated only with ascorbic acid and activated charcoal. A 16-year-old female voluntary ingested 3 grams of dapsone in an attempt of suicide and presented with desaturation and tachypnea. Lab findings were compatible with methemoglobinemia. After two days of treatment with ascorbic acid and activated charcoal, we observed the disappearance of desaturation and tachypnea. Methemoglobinemia can be treated with ascorbic acid and activated charcoal in limited resource settings.
format Online
Article
Text
id pubmed-9674526
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The African Field Epidemiology Network
record_format MEDLINE/PubMed
spelling pubmed-96745262022-11-29 Acute dapsone poisoning with methemoglobinemia: a case report El Hamzaoui, Hamza Chajai, Idriss El Ouazzani, Mohamed Chahidi Benhalima, Abdelkader El Arfaoui, Manal Alilou, Mustapha Pan Afr Med J Case Report Methemoglobinemia is a common complication of dapsone poisoning. Its´ treatment usually relies on methylene blue infusion. The aim of this study was to report a case of an acute dapsone poisoning with methemoglobinemia treated only with ascorbic acid and activated charcoal. A 16-year-old female voluntary ingested 3 grams of dapsone in an attempt of suicide and presented with desaturation and tachypnea. Lab findings were compatible with methemoglobinemia. After two days of treatment with ascorbic acid and activated charcoal, we observed the disappearance of desaturation and tachypnea. Methemoglobinemia can be treated with ascorbic acid and activated charcoal in limited resource settings. The African Field Epidemiology Network 2022-09-14 /pmc/articles/PMC9674526/ /pubmed/36451721 http://dx.doi.org/10.11604/pamj.2022.43.20.34069 Text en Copyright: Hamza El Hamzaoui et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
El Hamzaoui, Hamza
Chajai, Idriss
El Ouazzani, Mohamed Chahidi
Benhalima, Abdelkader
El Arfaoui, Manal
Alilou, Mustapha
Acute dapsone poisoning with methemoglobinemia: a case report
title Acute dapsone poisoning with methemoglobinemia: a case report
title_full Acute dapsone poisoning with methemoglobinemia: a case report
title_fullStr Acute dapsone poisoning with methemoglobinemia: a case report
title_full_unstemmed Acute dapsone poisoning with methemoglobinemia: a case report
title_short Acute dapsone poisoning with methemoglobinemia: a case report
title_sort acute dapsone poisoning with methemoglobinemia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674526/
https://www.ncbi.nlm.nih.gov/pubmed/36451721
http://dx.doi.org/10.11604/pamj.2022.43.20.34069
work_keys_str_mv AT elhamzaouihamza acutedapsonepoisoningwithmethemoglobinemiaacasereport
AT chajaiidriss acutedapsonepoisoningwithmethemoglobinemiaacasereport
AT elouazzanimohamedchahidi acutedapsonepoisoningwithmethemoglobinemiaacasereport
AT benhalimaabdelkader acutedapsonepoisoningwithmethemoglobinemiaacasereport
AT elarfaouimanal acutedapsonepoisoningwithmethemoglobinemiaacasereport
AT aliloumustapha acutedapsonepoisoningwithmethemoglobinemiaacasereport

Ejemplares similares