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The unilateral involution in the thymus of a 96-year-old male leads to the preservation of structural integrity in one thymic lobe, as assessed by the expression of medullar and cortical antigens and the presence of CD3+ cells
The process of thymic involution begins soon after birth and continues through adult life. Although evolutionary conserved in all vertebrates, the thymic involution has no defined kinetics. Little is known about the pace of its regression in humans, except that there is a marked increase of thymic i...
Autores principales: | Kanneganti, Pranuthi, Lyle, Joseph, Smith, Julia H., McGuire, Heather, Denlinger, Richaela, Simm, Malgorzata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674545/ https://www.ncbi.nlm.nih.gov/pubmed/36411931 http://dx.doi.org/10.1016/j.heliyon.2022.e11734 |
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