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A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case

In this paper, we develop and examine a mathematical model of human melioidosis transmission with asymptomatic cases to describe the dynamics of the epidemic. The basic reproduction number [Formula: see text] of the model is obtained. Disease-free equilibrium of the model is proven to be globally as...

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Detalles Bibliográficos
Autores principales: Engida, Habtamu Ayalew, Theuri, David Mwangi, Gathungu, Duncan, Gachohi, John, Alemneh, Haileyesus Tessema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674546/
https://www.ncbi.nlm.nih.gov/pubmed/36411894
http://dx.doi.org/10.1016/j.heliyon.2022.e11720
Descripción
Sumario:In this paper, we develop and examine a mathematical model of human melioidosis transmission with asymptomatic cases to describe the dynamics of the epidemic. The basic reproduction number [Formula: see text] of the model is obtained. Disease-free equilibrium of the model is proven to be globally asymptotically stable when [Formula: see text] is less than the unity, while the endemic equilibrium of the model is shown to be locally asymptotically stable if [Formula: see text] is greater than unity. Sensitivity analysis is performed to illustrate the effect of the model parameters influencing on the disease dynamics. Furthermore, numerical experiments of the model are conducted to validate the theoretical findings.