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A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case
In this paper, we develop and examine a mathematical model of human melioidosis transmission with asymptomatic cases to describe the dynamics of the epidemic. The basic reproduction number [Formula: see text] of the model is obtained. Disease-free equilibrium of the model is proven to be globally as...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674546/ https://www.ncbi.nlm.nih.gov/pubmed/36411894 http://dx.doi.org/10.1016/j.heliyon.2022.e11720 |
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author | Engida, Habtamu Ayalew Theuri, David Mwangi Gathungu, Duncan Gachohi, John Alemneh, Haileyesus Tessema |
author_facet | Engida, Habtamu Ayalew Theuri, David Mwangi Gathungu, Duncan Gachohi, John Alemneh, Haileyesus Tessema |
author_sort | Engida, Habtamu Ayalew |
collection | PubMed |
description | In this paper, we develop and examine a mathematical model of human melioidosis transmission with asymptomatic cases to describe the dynamics of the epidemic. The basic reproduction number [Formula: see text] of the model is obtained. Disease-free equilibrium of the model is proven to be globally asymptotically stable when [Formula: see text] is less than the unity, while the endemic equilibrium of the model is shown to be locally asymptotically stable if [Formula: see text] is greater than unity. Sensitivity analysis is performed to illustrate the effect of the model parameters influencing on the disease dynamics. Furthermore, numerical experiments of the model are conducted to validate the theoretical findings. |
format | Online Article Text |
id | pubmed-9674546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-96745462022-11-20 A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case Engida, Habtamu Ayalew Theuri, David Mwangi Gathungu, Duncan Gachohi, John Alemneh, Haileyesus Tessema Heliyon Research Article In this paper, we develop and examine a mathematical model of human melioidosis transmission with asymptomatic cases to describe the dynamics of the epidemic. The basic reproduction number [Formula: see text] of the model is obtained. Disease-free equilibrium of the model is proven to be globally asymptotically stable when [Formula: see text] is less than the unity, while the endemic equilibrium of the model is shown to be locally asymptotically stable if [Formula: see text] is greater than unity. Sensitivity analysis is performed to illustrate the effect of the model parameters influencing on the disease dynamics. Furthermore, numerical experiments of the model are conducted to validate the theoretical findings. Elsevier 2022-11-15 /pmc/articles/PMC9674546/ /pubmed/36411894 http://dx.doi.org/10.1016/j.heliyon.2022.e11720 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Engida, Habtamu Ayalew Theuri, David Mwangi Gathungu, Duncan Gachohi, John Alemneh, Haileyesus Tessema A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title | A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title_full | A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title_fullStr | A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title_full_unstemmed | A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title_short | A mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
title_sort | mathematical model analysis of the human melioidosis transmission dynamics with an asymptomatic case |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674546/ https://www.ncbi.nlm.nih.gov/pubmed/36411894 http://dx.doi.org/10.1016/j.heliyon.2022.e11720 |
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