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Observation of hapten-induced sensitization responses for the development of a mouse skin sensitization test, including the elicitation phase
The only official method that can detect the skin sensitizing potential of chemicals, including the elicitation response, is the OECD test guideline (TG) 406. However, this guideline uses guinea pigs, which requires complex procedures. Since a simple and complete test method for evaluating skin sens...
Autores principales: | Kamata, Ryo, Okawa, Yukiko, Hamaguchi, Yuto, Tabata, Soma, Terasaki, Masanori, Takeda, Kazuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674688/ https://www.ncbi.nlm.nih.gov/pubmed/36400912 http://dx.doi.org/10.1038/s41598-022-24547-1 |
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