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Cancer cell survival depends on collagen uptake into tumor-associated stroma
Collagen I, the most abundant protein in humans, is ubiquitous in solid tumors where it provides a rich source of exploitable metabolic fuel for cancer cells. While tumor cells were unable to exploit collagen directly, here we show they can usurp metabolic byproducts of collagen-consuming tumor-asso...
Autores principales: | Hsu, Kuo-Sheng, Dunleavey, James M., Szot, Christopher, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Feng, Yang, Lutz, Emily M., Koogle, Robert, Tomassoni-Ardori, Francesco, Saha, Saurabh, Zhang, Xiaoyan M., Zudaire, Enrique, Bajgain, Pradip, Rose, Joshua, Zhu, Zhongyu, Dimitrov, Dimiter S., Cuttitta, Frank, Emenaker, Nancy J., Tessarollo, Lino, St. Croix, Brad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674701/ https://www.ncbi.nlm.nih.gov/pubmed/36400786 http://dx.doi.org/10.1038/s41467-022-34643-5 |
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