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The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer

Cervical cancer is the fourth most frequently diagnosed and fatal gynecological cancer. 15–61% of all cases metastasize and develop chemoresistance, reducing the 5-year survival of cervical cancer patients to as low as 17%. Therefore, unraveling the mechanisms contributing to metastasis is critical...

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Detalles Bibliográficos
Autores principales: Mandal, Ranadip, Raab, Monika, Rödel, Franz, Krämer, Andrea, Kostova, Izabela, Peña-Llopis, Samuel, Medici, Gioele, Häupl, Björn, Oellerich, Thomas, Gasimli, Khayal, Sanhaji, Mourad, Becker, Sven, Strebhardt, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674771/
https://www.ncbi.nlm.nih.gov/pubmed/36399280
http://dx.doi.org/10.1007/s00018-022-04598-3

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