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The non-apoptotic function of Caspase-8 in negatively regulating the CDK9-mediated Ser2 phosphorylation of RNA polymerase II in cervical cancer
Cervical cancer is the fourth most frequently diagnosed and fatal gynecological cancer. 15–61% of all cases metastasize and develop chemoresistance, reducing the 5-year survival of cervical cancer patients to as low as 17%. Therefore, unraveling the mechanisms contributing to metastasis is critical...
Autores principales: | Mandal, Ranadip, Raab, Monika, Rödel, Franz, Krämer, Andrea, Kostova, Izabela, Peña-Llopis, Samuel, Medici, Gioele, Häupl, Björn, Oellerich, Thomas, Gasimli, Khayal, Sanhaji, Mourad, Becker, Sven, Strebhardt, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674771/ https://www.ncbi.nlm.nih.gov/pubmed/36399280 http://dx.doi.org/10.1007/s00018-022-04598-3 |
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