Cargando…
Plasma exosomal miR-122 regulates the efficacy of metformin via AMPK in type 2 diabetes and hepatocellular carcinoma
Metformin is a drug that has been applied in clinical use for many years for the treatment of type 2 diabetes mellitus (T2DM). It achieves its function through multiple targets and modulation of multiple signaling pathways. To date, the mechanism of the action of metformin is still not fully underst...
Autores principales: | Peng, Hui, Hou, Mei, Wu, Zixin, Wang, Jing, Zhou, Man, Zhuang, Xiangjin, Xing, Jiayu, Tao, Qianqian, Huang, Long, Zhou, Fuhai, Zhang, Shengming, Feng, Qiyu, Hou, Yilin, Yu, Qinsheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674877/ https://www.ncbi.nlm.nih.gov/pubmed/36411886 http://dx.doi.org/10.1016/j.heliyon.2022.e11503 |
Ejemplares similares
-
Metformin induces apoptosis of human hepatocellular carcinoma HepG2 cells by activating an AMPK/p53/miR-23a/FOXA1 pathway
por: Sun, Yunpeng, et al.
Publicado: (2016) -
Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
por: Lou, Guohua, et al.
Publicado: (2015) -
Improving the Detection of Hepatocellular Carcinoma Using Serum AFP Expression in Combination with GPC3 and Micro-RNA MiR-122 Expression
por: Li, Jian, et al.
Publicado: (2019) -
Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome
por: Udesen, Pernille Bækgaard, et al.
Publicado: (2020) -
Association of circulating exosomal miR-122 levels with BAT activity in healthy humans
por: Okamatsu-Ogura, Yuko, et al.
Publicado: (2019)