Disentangling autoproteolytic cleavage from tethered agonist–dependent activation of the adhesion receptor ADGRL3

Adhesion G protein-coupled receptor latrophilin 3 (ADGRL3), a cell adhesion molecule highly expressed in the central nervous system, acts in synapse formation through trans interactions with its ligands. It is largely unknown if these interactions serve a purely adhesive function or can modulate G p...

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Detalles Bibliográficos
Autores principales: Perry-Hauser, Nicole A., VanDyck, Max W., Lee, Kuo Hao, Shi, Lei, Javitch, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674912/
https://www.ncbi.nlm.nih.gov/pubmed/36244455
http://dx.doi.org/10.1016/j.jbc.2022.102594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674912/
https://www.ncbi.nlm.nih.gov/pubmed/36244455
http://dx.doi.org/10.1016/j.jbc.2022.102594

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