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Disentangling autoproteolytic cleavage from tethered agonist–dependent activation of the adhesion receptor ADGRL3
Adhesion G protein-coupled receptor latrophilin 3 (ADGRL3), a cell adhesion molecule highly expressed in the central nervous system, acts in synapse formation through trans interactions with its ligands. It is largely unknown if these interactions serve a purely adhesive function or can modulate G p...
Autores principales: | Perry-Hauser, Nicole A., VanDyck, Max W., Lee, Kuo Hao, Shi, Lei, Javitch, Jonathan A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674912/ https://www.ncbi.nlm.nih.gov/pubmed/36244455 http://dx.doi.org/10.1016/j.jbc.2022.102594 |
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