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Chloroquine-Induced Psychosis: A Case Report
The use of antimalarial drugs for prophylaxis is a widespread practice while traveling to underdeveloped nations, particularly those with a high malaria prevalence. Chloroquine is still one of the most commonly recommended antimalarials, either alone or in combination with others, for prophylaxis. H...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674931/ https://www.ncbi.nlm.nih.gov/pubmed/36415420 http://dx.doi.org/10.7759/cureus.30498 |
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author | Chaudhry, Hamzah E Khan, Somieya Jamil, Sidra Shaik, Tanveer Ahamad Ehsan Ullah, Saad Bseiso, Anan Sathish, Meenakshi Saleem, Faraz Ghaffari, Muhammad Abu Zar |
author_facet | Chaudhry, Hamzah E Khan, Somieya Jamil, Sidra Shaik, Tanveer Ahamad Ehsan Ullah, Saad Bseiso, Anan Sathish, Meenakshi Saleem, Faraz Ghaffari, Muhammad Abu Zar |
author_sort | Chaudhry, Hamzah E |
collection | PubMed |
description | The use of antimalarial drugs for prophylaxis is a widespread practice while traveling to underdeveloped nations, particularly those with a high malaria prevalence. Chloroquine is still one of the most commonly recommended antimalarials, either alone or in combination with others, for prophylaxis. However, its increased use over the past few decades has been associated with many adverse effects, including headaches, dizziness, vomiting, and diarrhea, as well as neuropsychiatric symptoms such as psychosis. Here, we discuss the case of a 30-year-old Asian man who, after starting a 500-milligram (mg) prophylactic dosage of chloroquine per week, developed psychotic symptoms. This case highlights the need to use chloroquine and other antimalarials with care, especially when beginning as a prophylactic measure with the lowest suggested dosage. |
format | Online Article Text |
id | pubmed-9674931 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-96749312022-11-21 Chloroquine-Induced Psychosis: A Case Report Chaudhry, Hamzah E Khan, Somieya Jamil, Sidra Shaik, Tanveer Ahamad Ehsan Ullah, Saad Bseiso, Anan Sathish, Meenakshi Saleem, Faraz Ghaffari, Muhammad Abu Zar Cureus Internal Medicine The use of antimalarial drugs for prophylaxis is a widespread practice while traveling to underdeveloped nations, particularly those with a high malaria prevalence. Chloroquine is still one of the most commonly recommended antimalarials, either alone or in combination with others, for prophylaxis. However, its increased use over the past few decades has been associated with many adverse effects, including headaches, dizziness, vomiting, and diarrhea, as well as neuropsychiatric symptoms such as psychosis. Here, we discuss the case of a 30-year-old Asian man who, after starting a 500-milligram (mg) prophylactic dosage of chloroquine per week, developed psychotic symptoms. This case highlights the need to use chloroquine and other antimalarials with care, especially when beginning as a prophylactic measure with the lowest suggested dosage. Cureus 2022-10-20 /pmc/articles/PMC9674931/ /pubmed/36415420 http://dx.doi.org/10.7759/cureus.30498 Text en Copyright © 2022, Chaudhry et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Chaudhry, Hamzah E Khan, Somieya Jamil, Sidra Shaik, Tanveer Ahamad Ehsan Ullah, Saad Bseiso, Anan Sathish, Meenakshi Saleem, Faraz Ghaffari, Muhammad Abu Zar Chloroquine-Induced Psychosis: A Case Report |
title | Chloroquine-Induced Psychosis: A Case Report |
title_full | Chloroquine-Induced Psychosis: A Case Report |
title_fullStr | Chloroquine-Induced Psychosis: A Case Report |
title_full_unstemmed | Chloroquine-Induced Psychosis: A Case Report |
title_short | Chloroquine-Induced Psychosis: A Case Report |
title_sort | chloroquine-induced psychosis: a case report |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674931/ https://www.ncbi.nlm.nih.gov/pubmed/36415420 http://dx.doi.org/10.7759/cureus.30498 |
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